Mitsunori Kirihata Selected Research

Boron Neutron Capture Therapy

1/2022	Dodecaborate Conjugates Targeting Tumor Cell Overexpressing Translocator Protein for Boron Neutron Capture Therapy.
1/2022	Dodecaborate-Encapsulated Extracellular Vesicles with Modification of Cell-Penetrating Peptides for Enhancing Macropinocytotic Cellular Uptake and Biological Activity in Boron Neutron Capture Therapy.
1/2022	Synthesis and cytotoxicity of the boron carrier pentagamaboronon-0-ol for boron neutron capture therapy against breast cancer.
12/2020	The Therapeutic Effects of Dodecaborate Containing Boronophenylalanine for Boron Neutron Capture Therapy in a Rat Brain Tumor Model.
9/2020	Antibody-Based Receptor Targeting Using an Fc-Binding Peptide-Dodecaborate Conjugate and Macropinocytosis Induction for Boron Neutron Capture Therapy.
1/2020	Synthesis and Evaluation of Dodecaboranethiol Containing Kojic Acid (KA-BSH) as a Novel Agent for Boron Neutron Capture Therapy.
12/2019	Cellular uptake evaluation of pentagamaboronon-0 (PGB-0) for boron neutron capture therapy (BNCT) against breast cancer cells.
1/2017	Evaluation of a novel sodium borocaptate-containing unnatural amino acid as a boron delivery agent for neutron capture therapy of the F98 rat glioma.
12/2015	Boron neutron capture therapy (BNCT) as a new approach for clear cell sarcoma (CCS) treatment: Trial using a lung metastasis model of CCS.
1/2015	The Anti-Proliferative Effect of Boron Neutron Capture Therapy in a Prostate Cancer Xenograft Model.

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Mitsunori Kirihata Research Topics

Disease

30	Neoplasms (Cancer) 01/2022 - 01/2003
10	Glioma (Gliomas) 12/2020 - 12/2005
8	Brain Neoplasms (Brain Tumor) 12/2020 - 07/2006
5	Breast Neoplasms (Breast Cancer) 01/2022 - 08/2019
5	Glioblastoma (Glioblastoma Multiforme) 12/2011 - 11/2003
2	Clear Cell Sarcoma 12/2015 - 03/2013
1	Neoplasm Metastasis (Metastasis) 12/2015
1	Prostatic Neoplasms (Prostate Cancer) 01/2015
1	Head and Neck Neoplasms (Head and Neck Cancer) 01/2015
1	Necrosis 09/2008
1	Hyperthermia 01/2003

Drug/Important Bio-Agent (IBA)

17	BoronIBA 01/2022 - 12/2005
7	SodiumIBA 01/2017 - 12/2005
5	Boron-10IBA 01/2022 - 05/2008
3	dodecaborateIBA 01/2022 - 12/2011
3	Therapeutic UsesIBA 12/2020 - 01/2011
3	Boron CompoundsIBA 09/2020 - 12/2005
3	Amino Acids FDA Link 01/2017 - 12/2011
2	LithiumIBA 01/2022 - 09/2020
2	Phenylalanine (L-Phenylalanine)FDA Link 12/2015 - 07/2009
2	Monoclonal AntibodiesIBA 03/2009 - 05/2008
2	Liposomes (Liposome)IBA 03/2009 - 05/2008
1	Proteins (Proteins, Gene)FDA Link 01/2022
1	AnionsIBA 01/2022
1	polyarginineIBA 01/2022
1	BoranesIBA 01/2022
1	Cell-Penetrating PeptidesIBA 01/2022
1	Antineoplastic Agents (Antineoplastics)IBA 01/2021
1	AmidesIBA 12/2020
1	IsotopesIBA 01/2015
1	AcidsIBA 12/2014
1	Bevacizumab (Avastin)FDA Link 03/2013
1	Angiogenesis InhibitorsIBA 03/2013
1	4-boronophenylalanineIBA 03/2013
1	Temozolomide (Temodar)FDA LinkGeneric 12/2011
1	PolyaminesIBA 12/2011
1	GelatinIBA 01/2011
1	AntibodiesIBA 03/2009
1	FluoridesIBA 09/2008
1	Transferrin (beta 2 Transferrin)IBA 05/2008
1	Bromodeoxyuridine (BrdU)IBA 01/2003
1	Cytochalasin BIBA 01/2003
1	Tirapazamine (SR 4233)IBA 01/2003
1	SuspensionsIBA 01/2003

Therapy/Procedure

30	Boron Neutron Capture Therapy 01/2022 - 11/2003
8	Radiotherapy 01/2022 - 11/2003
2	Therapeutics 09/2020 - 01/2011
2	Drug Therapy (Chemotherapy) 07/2009 - 01/2009
2	Intraperitoneal Injections 07/2006 - 01/2003
1	Neutron Capture Therapy 01/2017
1	Craniotomy 11/2003
1	Oral Administration 01/2003